IndraLab

Statements

COPS5 activates Proteasome. 3 / 3
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"Independently, IFIT proteins may modulate expression of negative regulators of the cell cycle, resulting in the accumulation of cells at the G 1 / S phase transition 60; ectopic expression of IFIT3 in U937 human myeloid cells resulted in sequestration of c-Jun activation domain binding protein-1 (JAB1), which limited ubiquitin and proteasome dependent degradation of cyclin dependent kinase inhibitor 1B (also known as p27 or KIP1)."
23237964
reach
"Indeed, ectopic expression of IFIT3 in U937 human myeloid cells resulted in the sequestration of JUN activation domain-binding protein 1 (JAB1; also known as COPS5), which limited ubiquitin- and proteasome-dependent degradation of cyclin-dependent kinase inhibitor 1B (also known as p27 and KIP1)."
23237964
reach
"Down-regulation of human CSN4 or CSN5 induced proteasome mediated degradation of the ubiquitin conjugating enzyme UBC3 and Cdc34."
20378537