Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ZUP1 leads to the ubiquitination of NLRP3. 1 / 1

| 1

➶

reach

"The study also showed that CAPE promotes the ubiquitination of NLRP3 through the inhibition of ROS and increases the level of interaction between NLRP3 and the E3 ligase Cullin 1, whereas it decreases the interaction between NLRP3 and CSN5 (a DUB), which together increases NLRP3 ubiquitination."

| PMC

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...