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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EGFR binds GRB2 and MET. 2 / 2

| 1 1

➶

reach

"On activation of certain RTKs such as EGFR and MET, Gab1 is recruited to the plasma membrane via interaction with EGFR bound Grb2 or directly with MET, followed by the phosphorylation of a number of tyrosine residues on Gab1."

26246598

➶

sparser

"Prior co-immunoprecipitation experiments provided indirect evidence that Grb2 is the primary target of 1 and that 1 was able to disrupt Grb2-EGFR and Grb2-c-Met interactions. xref , xref "

18989951

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...