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USP15 activates cell viability ovarian cancer cells expressing p53-R175H mutant protein. 1 / 1
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"Depletion of USP15 causes decreased cell viability of ovarian cancer cells expressing the p53-R175H mutant protein , suggesting that targeting USP15 in p53-R175H mutant-containing tumors would facilitate the inhibition of oncogenic mutant p53 and enhance cancer immunotherapy [ 81 ] ."