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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

KCNA5 increases the amount of uncoupling protein 2. 1 / 1

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"In oxLDL induced endothelial cell injury model, we further found that knockdown of KCNA5 gene attenuated, whereas overexpression of KCNA5 gene enhanced oxLDL induced endothelial morphological changes, ROS generation derived from NADPH oxidase and mitochondria, and the protein expression of uncoupling protein 2 (UCP2), a modulator of mitochondria derived ROS production XREF_BIBR, XREF_BIBR."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...