IndraLab

Statements

NFkappaB decreases the amount of CYLD. 3 / 3
| 3
reach
"However, a recent report showed that the loss of CYLD in keratinocytes of mice did not affect transcription induced by the classical p65-p50 NF-kappaB dimers but had clear effects on Bcl-3-linked p50- or p52 dependent gene regulation [XREF_BIBR]."
20414373
reach
"Thus, the present study revealed that, in bladder cancer, NF-kappaB can maintain its activity by establishing a feedback loop, in which NF-kappaB induced the expression of miR-130b, which consequently inhibited the expression of CYLD, which in turn was an endogenous inhibitor of NF-kappaB activation."
27391066
reach
"Interestingly, the reduced NF-kappaB activation in CYLD expressing macrophages limited the protective effect of IFN-gamma by reducing NF-kappaB-dependent signal transducers and activators of transcription-1 (STAT1) activation."
26834734