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UCHL1 bound to PRKN activates Alzheimer Disease. 1 / 1

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"Taken together, our studies show a causative link between the excessive mitochondrial turnover and the NH2htau induced in vitro neuronal death, suggesting that pathogenetic tau truncation may contribute to synaptic deterioration in AD by aberrant recruitment of Parkin and UCHL-1 to mitochondria making them more prone to detrimental autophagic clearance."

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UCHL1 bound to PRKN activates Alzheimer Disease. 1 / 1

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