IndraLab

Statements


TLR2 leads to the phosphorylation of USP10 on T674. 2 / 2
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reach
"Collectively, these results indicated that BCR and TLR2 synergistically enhance Akt activity and promote USP10 T674 phosphorylation located within the NLS domain and, therefore, the nuclear import of USP10, consequently inhibiting the AID degradation in the nucleus.Pam 3 Csk 4 helped to enhance the antibody response to the SARS-CoV-2 RBD nanoparticle vaccine Pam 3 Csk 4 has been used as a vaccine adjuvant."

reach
"Collectively, these results indicated that BCR and TLR2 synergistically enhance Akt activity and promote USP10 T674 phosphorylation located within the NLS domain and, therefore, the nuclear import of USP10, consequently inhibiting the AID degradation in the nucleus.Pam3Csk4 has been used as a vaccine adjuvant.59 To explore the effect of Pam3Csk4 on the SARS-CoV-2 RBD particle vaccine immune response, USP10-BWT and USP10-BKO mice were immunized with adjuvants in combination with the SARS-CoV-2 RBD particle vaccine."