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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PRL activates STAT5. 3 / 3

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bel

"We demonstrate that SOCS-7 inhibits prolactin (PRL), growth hormone (GH), or leptin (LEP) signaling mediated through STAT3 and STAT5"

15677474

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bel

"We first demonstrated that STAT5 and STAT3 could be activated by either hGH or hPRL in T-47D breast cancer cells."

11078803

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bel

"STAT3 is activated by many interleukins, IFNg,c-Kit, SCF, GCSF and EGF (for a review, see Heinrich et al., 2003) similar to STAT5, which is activated in particular by IL-2 and IL-7, Prolactin, G-CSF and GM-CSF."

15694833

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...