IndraLab

Statements

USP14 binds UCHL5 and RP. 6 / 6
| 6
sparser
"Apart from the integral DUB — Rpn11, there are other pDUBs — USP14 and UCHL5, which bind transiently to the 19S RP during the degradation process [ xref , xref ]."
33729481
sparser
"Similar to the mode of action exerted by b-AP15, this set of compounds inhibits activity of two DUBs, UCHL5 and USP14 that are associated with 19S RP, and do not affect non-proteasomal DUBs [ xref ]."
26077642
sparser
"Both USP14 and UCHL5 bind reversibly to the 19S RP and are implicated in cancer [48] ."
26077642
sparser
"It selectively inhibits the activity of two DUBs, UCHL5 and USP14 that are associated with 19S RP while not affecting the non-proteasomal DUBs."
26077642
sparser
"Both USP14 and UCHL5 bind reversibly to the 19S RP and are implicated in cancer [ xref ]."
26077642
sparser
"Similar to the mode of action exerted by b-AP15, this set of compounds inhibits activity of two DUBs, UCHL5 and USP14 that are associated with 19S RP, and do not affect non-proteasomal DUBs [75] ."
26077642