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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Modified USP7 leads to the ubiquitination of MDM2. 2 / 2

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"Disruption of the USP7 gene is also lethal to p53 wt cells, as loss of USP7 expression enhances the auto-ubiquitination of MDM2 leading to its degradation, resulting in p53 stabilization and apoptosis."

26971997

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"Disruption of the USP7 gene is also lethal to p53 wild-type (WT) cells, as loss of USP7 expression enhances the auto-ubiquitination of MDM2 leading to its degradation, resulting in p53 stabilization a[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

26971997

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...