IndraLab

Statements

Mutated USP26 activates Lys-Ser. 2 / 2
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"Thus, some KS should originate from XY spermatozoa, and paternal USP26 mutations increase the risk of producing KS offspring."
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"Consistent with our mouse results, a clinical study shows that some USP26 variations increase the proportion of XY aneuploid spermatozoa in fertile men, and we identified two families with KS offspring wherein the father of the KS patient harbored a USP26 mutated haplotype, further supporting that paternal USP26 mutation can cause KS offspring production."
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