IndraLab

Statements


UCHL1 inhibits ZUP1. 2 / 2
| 2

eidos
"Thus , the finding in this study that UCHL1 / L3 inhibition is not as efficient in blocking viral replication as general inhibition of proteasome function or knockdown of ubiquitin is likely attributed to incomplete inhibition of DUBs by UCHL1 / L3 inhibitors ."

eidos
"Thus , it is speculated that DUB inhibition by UCHL1 / L3 inhibitors alone , in the absence of apparent inhibition of protein degradation , is not sufficient enough to block viral replication ."