IndraLab

Statements


| 1

reach
"These three JAMM domain DUBs are : Rpn11 in yeast (POH1 in humans) XREF_BIBR - XREF_BIBR, a subunit of the proteasome that cleaves ubiquitin chains from substrate proteins that are being degraded by the proteasome; CSN5, a subunit of the COP9 signalosome XREF_BIBR which cleaves Nedd8 (Neural Precursor Cell Expressed, Developmentally Down-regulated 8, a ubiquitin like protein) conjugates; and AMSH (associated molecule with the SH3 domain of STAM) a deubiquitinating enzyme involved in endocytosis XREF_BIBR."