IndraLab

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USP7 activates E1B-55K. 2 / 2
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"However, considering known functions of USP7 in gene expression control through regulation of histone proteins and the known relationship between adenoviral gene expression activity and the chromatinization of the adenoviral genome inside the nucleus of infected cells, it is also likely that USP7 mediated E1B-55K stability might be exerted through a mechanism other than direct deubiquitination of E1B-55K XREF_BIBR - XREF_BIBR."
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"However, during the course of this study, it became clear that USP7 not only specifically targets E1B-55K, but also exerts positive effects on other early proteins (and late proteins)."
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