IndraLab

Statements

UCHL1 activates angiogenesis. 3 / 4
| 3
reach
"Thus, a positive feedback loop between UCHL1, HIF-1alpha, and POSTN might be proposed where UCHL1 may promote angiogenesis directly via HIF-1alpha stabilization and indirectly via POSTN upregulation."
28472177
reach
"This study also showed that UCH-L1 promotes angiogenesis of HUVECs, as well as invasion in cancer cells, by up-regulating ROS by deubiquitination of NOX4, suggesting that UCH-L1 plays a key role in angiogenesis of HUVECS by regulating ROS levels by deubiquitination of NOX4."
29128359
reach
"These immunoprecipitation studies confirm that UCH-L1 deubiquitinates NOX4 in HUVECs, and suggest that UCH-L1 is involved in ROS mediated angiogenesis in HUVECs by modulating NOX4 activity via deubiqu[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
29128359