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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach

CCDC88A binds EGF and EGFR. 1 / 1
| 1
"Our working model ( xref ) is that after EGF stimulation, GIV initially binds activated EGFR and activates Gαi3 and Akt to regulate EGFR signaling and cell migration at the PM ( xref ), and later GIV binds Gαs at EEA1 endosomes to facilitate EEA1 endosome maturation and down-regulation of proliferative signaling from EEA1 endosomes as shown in the present work."