A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

IndraLab

Statements

databases
phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach
reading

CCDC88A binds EGF and EGFR. 1 / 1
| 1
sparser
"Our working model ( xref ) is that after EGF stimulation, GIV initially binds activated EGFR and activates Gαi3 and Akt to regulate EGFR signaling and cell migration at the PM ( xref ), and later GIV binds Gαs at EEA1 endosomes to facilitate EEA1 endosome maturation and down-regulation of proliferative signaling from EEA1 endosomes as shown in the present work."