IndraLab

Statements


USP7 decreases the amount of CD274. 3 / 3
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reach
"As USP7 expression was positively correlated with PD-L1 expression in human GC tissues and abrogation of USP7 decreased the expression of PD-L1 in different GC cell lines, we next asked how USP7 regulates the PD-L1 expression."

reach
"As USP7 abrogation can decrease the expression of PD-L1 without impacting on its mRNA level, and PD-L1 was reported to be ubiquitinated and subjected to proteasome mediated degradation XREF_BIBR, XREF_BIBR, whether USP7 erases the ubiquitination of PD-L1 needs to be answered."

reach
"All these results indicate that USP7 abrogation can decrease the expression level of PD-L1 in GC cells."