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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SCN8A leads to the dephosphorylation of TLR4. 1 / 1

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"Moreover, MED suppressed NF-kappaB activation by blocking IkappaB-alpha (IkappaB-alpha) degradation and inhibited the phosphorylation of ERK 1/2 and toll like receptor 4 (TLR4) expression, but had no effect on the phosphorylation of JNK, and p38."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...