IndraLab
Statements
reach
"XREF_BIBR USP7 can deubiquitinate various tumor suppressors (p53, PTEN, FOXO, and claspin), E3 ligases (MDM2 and MDMX and viral protein ICP0), as well as chromatin associated proteins (histone H2B, UHRF1, and Tip60); therefore, it regulates important cellular processes involved in the tumorigenesis."