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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Kinase-active STK11 inhibits MTOR. 2 / 2

2 |

➶

bel

"TSC1/2 can also be targeted and activated by LKB1 tumor suppressor protein, activating the AMPdependent kinase"

17210675

➶

bel

"In addition to effects on metabolism, LKB1 has also been suggested to possess a variety of potentially tumor-suppressive functions such as inhibition of mammalian target of rapamycin, regulation of cell polarity, inhibition of the cell cycle, and activation of p53 (4)."

18483235

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...