IndraLab

Statements

ASXL1 binds ASXL2 and BAP1. 3 / 3
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"Although both ASXL1 and ASXL2 have been identified to bind to BAP1, recent biochemical characterization of BAP1 complexes by xref suggest that BAP1 forms two mutually exclusive complexes with ASXL1 and ASXL2."
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"Depletion of the PHD fingers did not affect the stability of ASXL1 or ASXL2, or the interaction between ASXL1, ASXL2, and BAP1 (Additional file xref : Fig. S2A, B)."
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"Proteomic analysis of BAP1 interacting partners using this system revealed that BAP1 interacts with ASXL1 and ASXL2 in vivo as well as host cell factor 1 (HCF-1), O-GlcNAc transferase (OGT), and Forkhead box protein K1/2 (FOXK1/2) ( xref )."
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