IndraLab

Statements

UCHL5 activates cell migration. 13 / 13
| 2 11
reach
"UCHL5 is also overexpressed in hepatocellular carcinoma, and was shown to promote cell migration and invasion 57 ."
28959952
eidos
"A high UCHL5 expression level predicts early recurrence and promotes cell migration and invasion in hepatocellular carcinoma ( HCC ) 12 ."
33046988
reach
"In vitro, we discovered that UCH37 could promote cell migration and invasion."
23220010
reach
"Furthermore, we discovered that UCH37 could promote cell migration and invasion in HCC cell lines through interacting and deubiquitinating PRP19, an essential RNA splicing factor.Tumor specimens used [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"Fang Y et al. found UCH-L5 promotes cell migration and invasion via interacting and deubiquitinating splicing factor PRP19 in hepatocellular carcinoma [XREF_BIBR]."
29371935
eidos
"UCHL5 is also overexpressed in hepatocellular carcinoma , and was shown to promote cell migration and invasion57 ."
28959952
reach
"Collectively, this study demonstrated that UCH37 could promote cell migration and invasion in HCC cell lines through interacting and deubiquitinating PRP19, and suggested that UCH37 could be a novel predictor for HCC recurrence after curative resection."
23220010
reach
"Yet UCH37 knockdown significantly impairs cell migration in pancreatic cancer cell lines through the abolition of the TGF-beta-induced expression of MMP-2 and PAI-1, which are thought to play a key ro[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"All of the evidences suggest that the up-regulation of UCH37 may play an important role in oncogenesis through promoting some proto-oncogenes ' expression and stem cell like characteristics in the cel[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"A high UCHL5 expression level predicts early recurrence and promotes cell migration and invasion in hepatocellular carcinoma (HCC) XREF_BIBR."
33046988
reach
"UCHL5 is also overexpressed in hepatocellular carcinoma, and was shown to promote cell migration and invasion ."
28959952
reach
"We believe that UCH37 could be a good diagnostic and therapeutic target for controlling HCC recurrence, and further investigations in this field are needed.This study provided evidence for the first t[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"Intriguingly, knock-down of PRP19 reduced the capability of cell migration and invasion, compare with the control cells, suggesting that UCH37 exerted its effects at least in part by deubiquitinating [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010