IndraLab

Statements

UCHL5 activates cell migration. 13 / 13
| 2 11
eidos
"UCHL5 is also overexpressed in hepatocellular carcinoma , and was shown to promote cell migration and invasion57 ."
28959952
reach
"Fang Y et al. found UCH-L5 promotes cell migration and invasion via interacting and deubiquitinating splicing factor PRP19 in hepatocellular carcinoma [XREF_BIBR]."
29371935
reach
"UCHL5 is also overexpressed in hepatocellular carcinoma, and was shown to promote cell migration and invasion ."
28959952
reach
"We believe that UCH37 could be a good diagnostic and therapeutic target for controlling HCC recurrence, and further investigations in this field are needed.This study provided evidence for the first t[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"Furthermore, we discovered that UCH37 could promote cell migration and invasion in HCC cell lines through interacting and deubiquitinating PRP19, an essential RNA splicing factor.Tumor specimens used [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"However, knockdown of UCH37 completely abolished cell migration and, conversely, cells overexpressing UCH37 migrated much more rapidly ( Fig. 5 A)."
21187158
reach
"The wound-healing assay results reveal that UCHL5 overexpression promotes cell migration, as seen in Figure 3D."
36428630
reach
"A high UCHL5 expression level predicts early recurrence and promotes cell migration and invasion in hepatocellular carcinoma (HCC) XREF_BIBR."
33046988
reach
"Yet UCH37 knockdown significantly impairs cell migration in pancreatic cancer cell lines through the abolition of the TGF-beta-induced expression of MMP-2 and PAI-1, which are thought to play a key ro[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"All of the evidences suggest that the up-regulation of UCH37 may play an important role in oncogenesis through promoting some proto-oncogenes ' expression and stem cell like characteristics in the cel[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"Intriguingly, knock-down of PRP19 reduced the capability of cell migration and invasion, compare with the control cells, suggesting that UCH37 exerted its effects at least in part by deubiquitinating [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23220010
reach
"Our group found that UCH37, a novel predictor for HCC recurrence, promoted cell migration and invasion via up-regulated PRP19 (pre-mRNA processing factor 19) [75] ."
26193663
eidos
"A high UCHL5 expression level predicts early recurrence and promotes cell migration and invasion in hepatocellular carcinoma ( HCC ) 12 ."
33046988