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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Transcriptionally active PPARG activates cell differentiation. 3 / 3

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"Activation of PPARG also induces differentiation of colon cancer cells"

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"PPARg was shown to be a differentiation-promoting transcription factor in adipogenesis (Fajas et al., 2001; Rosen and Spiegelman, 2001). Both caveolin-1 and -2 levels increase dramatically during differentiation of preadipocytes to adipocytes (Scherer et al., 1994, 1997) Human MCF-7 breast adenocarcinoma and human HT-29 colon adenocarcinoma cells"

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"Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a nuclear receptor for eicosanoids that promotes differentiation of human epithelial and mesenchymal cells in vitro and in vivo."

12813462

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...