IndraLab

Statements

CYLD inhibits sub. 3 / 3
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"We also checked in both lines of transgenic mice, that, as expected, the CYLD C/S mutant was catalytically inactive and inhibited the DUB function of the endogenous CYLD, as we previously described that occurred in the epidermal HaCaT-CYLD C/S and PDVC57-CYLD C/S cells [XREF_BIBR, XREF_BIBR] (XREF_SUPPLEMENTARY)."
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"Similarly, CYLD Ser418 phosphorylation upon co-expression of IKKepsilon was found to decrease its DUB activity."
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"Interestingly, phosphorylation of CYLD has been shown to inhibit its DUB activity XREF_BIBR - XREF_BIBR."
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