IndraLab

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RPL5 binds TP53 and MDM2. 4 / 4
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sparser
"RRM1 is Required for Interaction with the RPL5-MDM2 Complex, p53 Induction, and OIS."

sparser
"For example, the p53-Mdm2 complex interacts with ribosomal protein L5 and 5S rRNA (Marechal et al., 1994) , and p53 was shown to bind to DNA sequences near replication origins in the ribosome gene cl[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"On the one hand, SRSF1 overexpression leads to the formation of a nucleoplasmic complex with the ribosomal protein RPL5 and the E3-ubiquitin ligase MDM2, which normally ubiquitylates the p53 tumor-suppressor protein leading to its proteolytic degradation [ xref ]."

No evidence text available