IndraLab

Statements

CACNA1A inhibits isocyanic acid. 11 / 11
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sparser
"Its vascular selectivity may be at least in part related to the marked voltage-dependent inhibition of ICa."
8773452
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"These results indicate that the voltage-dependent inhibition of ICa by semotiadil may be due to binding of the ionized drug during the inactivated state and also inhibition of the transition from the inactivated to the resting state."
8483295
sparser
"Cells loaded with these Ca chelators did not show any symptom of voltage dependent inactivation of ICa."
2409519
sparser
"This voltage-dependent block of iK is, therefore, opposite to the voltage-dependent inhibition of iCa produced by these compounds, where block of iCa is accentuated at positive membrane potentials."
2409272
sparser
"Barbiturates accelerated the decay phase of ICa at high concentrations (1 X 10(-4) to 3 X 10(-3) M), at which concentrations double-pulse experiments showed the increased rate of a voltage-dependent inactivation of ICa."
6100847
sparser
"The time constants rf and r~ may represent Ca2+- and voltage-dependent inactivation of Ica, respectively, whereas IB~ appeared to inactivate only by a voltage-dependent mechanism."
8549816
sparser
"Analysis of the It-Vc curve showed that cAMP enhanced both Ca(2+)-dependent and voltage-dependent inactivation of ICa."
1316558
sparser
"It is concluded that the acceleration of the decay phase of ICa by barbiturates may be due to the increased rate of the voltage-dependent inactivation of ICa."
6100847
sparser
"Interestingly, the voltage-dependent inactivation of INa and ICa seemed to be more stable at high pressures compared to the activation parameters, as no significant changes were found up to a 20-MPa treatment."
12172643
sparser
"In all three genotypes, the voltage-dependent inactivation and deactivation of iCa were similar."
14594987
sparser
"These findings suggest that overdrive suppression in the SA node is, in part at least, the result of a rate- and voltage-dependent inactivation of iCa."
8945930