IndraLab

Statements

COPS5 increases the amount of RAD51. 4 / 4
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"Jab1 and CSN5 knockdown not only decreased the level of Rad51 but also affected its activity."
22867945
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"Jab1 knockdown not only decreased the protein level of Rad51 but also affected its repair function, as shown on XREF_FIG, which compares a reduced Rad51 foci formation in Jab1 siRNA treated cells with the Rad51 foci in control siRNA treated cells after gamma-IR."
20802511
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"Inhibition of Jab1 and COPS5 not only decreases Rad51 level but also impaired its activity, resulting in an increase in cell apoptosis after DNA stimulus."
29535627
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"These results suggested that Jab1 knockdown causes reduction in Rad51 gene expression, leading to a decreased ability of cells to repair DNA lesions through a homologous recombination pathway."
20802511