IndraLab

Statements

Sodium atom inhibits KCNH2. 6 / 6
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sparser
"Inhibition of WT HERG by Na(+)(o) was not strongly dependent on the voltage during activating pulses."
12356854
sparser
"The relief of Na + o inhibition of WT HERG by Ba 2+ o ( xref ) could conceivably be explained by competition of the two cations for a common site."
12356854
sparser
"Further, Ba 2+ o was found to relieve Na + o inhibition of HERG ( xref ), and Na + o was able to protect against onset of Ba 2+ o effects ( xref )."
12356854
sparser
"The time constants of the hERG Na + current inactivation (τ inact ) were plotted against the test voltages ( xref )."
16769794
sparser
"To examine the voltage dependence of the hERG Na + current inactivation, a depolarizing step to 70 mV for 250 ms was used to induce the peak Na + current."
16769794
sparser
"The predictable outward tail currents recorded from WT channels in those conditions (data not shown) were small due to the fact that extracellular sodium potently inhibits hERG channels when extracell[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
21806934