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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

EGFR bound to ERBB2 activates AKT. 2 / 2

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"On the other hand, TGFalpha induced HER2 and EGFR heterodimers and activated both AKT and Erk1/2 (XREF_SUPPLEMENTARY)."

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reach

"For example the ErbB1 and ErbB2 heterodimer was found to activate AKT, which in turn blocks p53 -- a master regulator of apoptosis 47."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...