IndraLab

Statements

AXIN1 binds UCHL5. 8 / 8
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sparser
"These results imply that the interaction between Axin1 and UCHL5 is most likely mediated by the coordination of multiple domains of Axin1 protein."
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No evidence text available
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"Coincidentally, UCHL5 interacts with Axin1 through multiple domains (1–705; RGS, GSK3ß, ß-catenin, and PP2A binding domain) where intra-molecular interactions arise."
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"Co-immunoprecipitation (Co-IP) analysis revealed that UCHL5 interacted with Axin1 in both ectopically and endogenously expressed conditions (Fig.  xref c,d)."
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"In vitro binding assay using recombinant proteins demonstrated that UCHL5 directly interacts with Axin1 protein (Fig.  xref f)."
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"We then examined if UCHL5 physically interacts with Axin1, which is a scaffolder of the ß-catenin destruction complex."
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biogrid
No evidence text available
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biogrid
No evidence text available
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