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ATXN3 activates Huntington Disease. 1 / 1

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"Expansion of polyQ domains in huntingtin and the deubiquitinase ataxin-3 causes Huntington's disease characterized by loss of striatal neurons and hence changes in mood and personality, defective motor coordination, and involuntary movements and type-3 spinocerebellar ataxia (SCA3), a form of neurodegeneration in the striatum and cerebellum, respectively [104] ."

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ATXN3 activates Huntington Disease. 1 / 1

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