IndraLab

Statements



sparser
"To this end, some NSAIDs inactivate the transcription factors NF-κB and activator protein-1 (e.g. aspirin and COX-2-selective inhibitors) or activate the peroxisome proliferator-activated receptor-γ (PPAR-γ; e.g. indomethacin and ibuprofen)."

sparser
"NSAIDs are able to inactivate the transcription NF-kB and activator protein-1 (AP-1), critically involved in the induction of multiple inflammatory gene products involved in the inflammatory response (i.e. iNOS, TNF-α)."