Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Kinase-active TGFBR2 activates SMAD2. 5 / 5

3 2 |

➶

bel

"TGFbeta markedly and specifically decreases both mRNA and protein levels of a HIF-1alpha-associated prolyl hydroxylase (PHD), PHD2, through the Smad signaling pathway."

16815840

➶

bel

"TGF? binds to TGF? receptor II on T cells, which leads to the recruitment of TGF? receptor I to the complex and activation of cytoplasmic transcription factors SMAD2 and SMAD3. "

20656683

➶

bel

"Modified assertion"

12421823

➶

bel

"Modified assertion"

12421823

➶

bel

"TGF? binds to TGF? receptor II on T cells, which leads to the recruitment of TGF? receptor I to the complex and activation of cytoplasmic transcription factors SMAD2 and SMAD3."

20656683

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...