IndraLab

Statements


MTORC1 inhibits UCHL1. 5 / 5
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reach
"Inhibition of mTORC1 results in up-regulation of Uchl1 and is associated with the shuttling of Uchl1 from the nucleus to the cytoplasm [46]."

reach
"Antisense Uchl1 function is under the control of stress signalling pathways, as mTORC1 inhibition by rapamycin causes an increase in UCHL1 protein that is associated to the shuttling of antisense Uchl1 RNA from the nucleus to the cytoplasm."

reach
"Under normal physiological conditions, AS Uchl1 is enriched in the nucleus, and upon rapamycin treatment, inhibition of mTORC1 triggers the transport of AS Uchl1 to the cytoplasm, which then targets the overlapping Uchl1 mRNA to active polysomes for cap independent translation."

eidos
"Inhibition of mTORC1 results in up-regulation of Uchl1 and is associated with the shuttling of Uchl1 from the nucleus to the cytoplasm [ 46 ] ."

reach
"For example, TORC1 inhibition by rapamycin causes the shuttling of Uchl1 lncRNA from the nucleus to the cytoplasm."