IndraLab

Statements

CDK1 phosphorylates NPM1 on T237. 15 / 15
1 2 6 1 | 2 3
hprd
No evidence text available
17287340
reach
"CDK1 phosphorylation of NPM at threonine 234/237 is critical in HCC migration and invasion."
26536659
rlimsp
"CDK1 phosphorylation of NPM at threonine 234/237 is critical in HCC migration and invasion."
26536659
rlimsp
"NPM phosphorylation at Thr234/237 is the only NPM phosphorylation site that spotted on this phospho-peptide array which is specifically phosphorylated by CDK1 (Figure 1B)."
26536659
hprd
No evidence text available
17287340
hprd
No evidence text available
11278991
biopax:phosphositeplus
No evidence text available
rlimsp
"NPM phosphorylation at Thr234/237 is the only NPM phosphorylation site that spotted on this phospho-peptide array which is specifically phosphorylated by CDK1 (Figure 1B). Western blot analysis confirmed elevated p-NPM-Thr234/237 and CDK1 in PLC/PRF/5-LM cells using a phospho-NPM (Thr234/237) specific antibody (Biolegend) (Figure 1C)."
26536659
signor
"Both subtypes of B23 proteins were phosphorylated during mitosis by cyclin B/cdc2. The RNA binding activity of B23.1 was repressed through cyclin B/cdc2-mediated phosphorylation at specific sites in B23. Thus, the RNA binding activity of B23.1 is stringently modulated by its phosphorylation and subtype association."
12058066
hprd
No evidence text available
20068231
reach
"10 CDK1 phosphorylates NPM at the beginning of mitosis at Thr199 and Thr234/237, resulting in inhibition of NPM RNA binding activity."
25908633
hprd
No evidence text available
20068231
signor
"We further demonstrate that phospho-mkk1/mkk2 antibodies recognize npm on the c-terminal region, which is phosphorylated by cdc2 (cell division control kinase-2) during g2/m-phase. biochemical and immunocytochemistry analyses verified that the phospho-mkk1/mkk2 antibodies cross-reacted with npm that was phosphorylated at thr234 and thr237 during g2/m-phase, which are the same sites that are targeted by cdc2 (cell division cycle protein-2) during mitosis."
14670079
phosphoelm
No evidence text available
14670079
hprd
No evidence text available
11278991