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Sirolimus decreases the amount of tyrosine-phosphorylated IRS1. 1 / 1
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reach
"Rapamycin inhibited the inflammatory stress induced p-mTOR and p-S6K expression, reduced the levels of serine phosphorylated IRS-1, and increased total IRS-1 and tyrosine phosphorylated IRS-1 expression (XREF_FIG)."