IndraLab

Statements

RNF4 binds USP11. 5 / 5
1 | 4
sparser
"After RNF4-FLAG IP, we found that endogenous USP11 interacted specifically with RNF4, with no signal detectable in the control ( xref )."
25969536
sparser
"Additionally, a potential effect of the DNA damaging agent methyl methanesulfonate (MMS) on the interaction between RNF4 and USP11 was investigated, as MMS is known to cause disassembly of the nuclear bodies harboring RNF4 ( xref )."
25969536
sparser
"In agreement with the mass spectrometry findings, free SUMO was detected only in the total lysates, a direct result of the SENPs removing all SUMO from target proteins following lysis, indicating that the interaction between USP11 and RNF4 is SUMOylation-independent ( xref )."
25969536
biogrid
No evidence text available
25969536
sparser
"There was no indication that the interaction between RNF4 and USP11 is disrupted upon treating the cells with MMS."
25969536