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BAP1 activates IL1B. 1 / 1
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"This study showed that the snake venom metalloprotease (SVMP) BaP1 activates FLSs to produce PGE 2 by a mechanism dependent on COX-2, mPGES-1 and iPLA 2 s. BaP1 also induces IL-1beta release, which up-regulates the production of PGE 2 at a late stage of the stimulation."