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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

NGF bound to TrkA receptors activates NTRK1. 1 / 1

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"To exert its effects, NGF selectively binds to its high affinity TrkA receptors, located at the plasma membrane of responsive cells, which causes TrkA receptors to form homodimers and activates the intrinsic tyrosine kinase activity of the receptor resulting in autophosphorylation of receptor subunits."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...