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USP15 activates signal transduction. 11 / 11
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"14 We demonstrate herein, for the first time, that USP15 can directly modulate wound healing by stabilizing TBR1 and maintaining the TGF-β signaling pathway, which represents a novel regulatory mechan[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In summary, our study demonstrates that USP15 can activate the NF-κB signaling pathway through BRCC3, thus enhancing the proliferation, migration, and invasiveness of bladder cancer cells."
38656882
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"Furthermore, USP15 promoted cell proliferation, invasion, and EMT progression via the Wnt/β-catenin signaling pathway in vitro and promoted the growth of GC cells in vivo."
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"53 Upregulation of USP15 could activate the NF‐κB signaling pathway, which might be involved in CAA pathology."
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"USP15 induced bladder cancer progression through reducing the degradation of BRCC3, thereby regulating the classical NF-κB signaling pathway."
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"USP15 modulates various signal transduction pathways, including the transforming growth factor-beta (TGF-beta), NF-kappaB, and Wnt-beta-catenin pathways; however, a role for USP15 in the IFN mediated antiviral innate immune response has not yet been described."
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"] In addition to preventing signaling proteins from degradation by removing K48-linked polyubiquitin chains , USP15 was shown to upregulate RLR signal transduction by indirectly attaching K63-linked polyubiquitin chains on RIG-I ."
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"USP15 can promote the proliferation and invasiveness of bladder cancer by mediating the NF-kappaB signaling pathway."
38656882
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"[180] In addition to preventing signaling proteins from degradation by removing K48 linked polyubiquitin chains, USP15 was shown to upregulate RLR signal transduction by indirectly attaching K63 linked polyubiquitin chains on RIG-I."
33511009
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"Herein, we first revealed that USP15 could promote wound healing by enhancing the proliferation and migration of HDFs and activating the TGF-β signaling pathway, thereby providing a novel therapeutic [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
30980801
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"USP15 can activate NF-kappaB signaling pathway via BRCC3, thereby promoting the growth, migration and invasiveness of bladder cancer."
38656882