IndraLab

Statements


EIF3H binds M. 3 / 3
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"We resorted to surface plasmon resonance assays to obtain further confirmation of a direct interaction between eIF3h and M, and to determine the characteristics of such an interaction."

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"This result allowed us to put forth the hypothesis that translation initiation on factor dependent mRNAs could be inhibited by RV M protein, by a mechanism that involves an interaction between M and eIF3h."

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"If it is the interaction between M and eIF3h that inhibits canonical initiation of protein synthesis, this inhibition should be overcome when the role of eIF3 in translation initiation is different."