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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP51 activates recruitment RNF168 53BP1 BRCA1 DSBs. 1 / 1

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"Similar to the DGCR8-knockdown effects ( Fig. 3a , b , f ) , knockdown of USP51 not only decreased HR and NHEJ repair efficiency in LM2-DRR cells ( Fig. 5e and Supplementary Fig. 5c , d ) , but also abrogated the recruitment of RNF168 , 53BP1 , and BRCA1 to DSBs after radiation treatment , without affecting the recruitment of MDC1 and RNF8 ( Fig. 5f and Supplementary Fig. 6 ) ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...