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TAC1 binds CACNA1A, CHI3L1, and α3. 1 / 1
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"The amylospheroids, amyloid β-protein (Aβ) oligomers typically found in postmortem brains of Alzheimer’s disease patients, can interact with α3-NKA impairing its activity, in turn leading to the activation of voltage-dependent calcium channels, mitochondrial abnormalities, and neurodegeneration ( xref ) (Figure xref )."