IndraLab

Statements

CDK1 phosphorylates USP1 on S313. 5 / 5
1 | 1 2 1
sparser
"Similarly close family member of Usp12, Usp1 is also phosphorylated at S313 by CDK1 during mitosis, this modification is required for its interaction with Uaf-1 as it lies within the Uaf-1 binding region (amino acids 235-408)."
25962961
reach
"In general, USP1 is phosphorylated by CDK1 at S313, and then binding with WDR48 for activation."
32951278
rlimsp
"We further demonstrated that CDK1 is responsible for Ser313 phosphorylation, and protein phosphatase treatment of USP1 can lead to inactivation of USP1/UAF1."
23116119
sparser
"In general, USP1 is phosphorylated by CDK1 at S313, and then binding with WDR48 for activation. xref As previously reported, USP1 could be degraded by APC/C Cdh1 during G1 phase."
32951278
biopax:phosphositeplus
No evidence text available