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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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EIF3F inhibits Atrophy. 3 / 4

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"Genetic blockade of eIF3f expression induced atrophy."

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"Genetic activation of eIF3f induces hypertrophy associated with an increase in phosphorylation of mTORC1 substrates S6K1 and 4E-BP1, and limits atrophy by increasing expression of muscle structural proteins during starvation (Csibi et al., 2010)."

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"In contrast, genetic blockade of eIF3f induces myotubes atrophy associated with a decrease in the phosphorylation of mTORC1 substrates (Csibi et al., 2010)."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

EIF3F inhibits Atrophy. 3 / 4

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