IndraLab

Statements


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"Genetic blockade of eIF3f expression induced atrophy."

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"Genetic activation of eIF3f induces hypertrophy associated with an increase in phosphorylation of mTORC1 substrates S6K1 and 4E-BP1, and limits atrophy by increasing expression of muscle structural proteins during starvation (Csibi et al., 2010)."

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"In contrast, genetic blockade of eIF3f induces myotubes atrophy associated with a decrease in the phosphorylation of mTORC1 substrates (Csibi et al., 2010)."