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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ESR1 decreases the amount of IRS1. 1 / 2

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"Because I3C can stimulate the proteasome mediated degradation of ERalpha that leads to the loss of ERalpha expression, the ablation of ERalpha by I3C is predicted to disrupt estrogen dependent IGF1R and IRS1 gene expression."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...