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UCHL5 activates Osteosarcoma. 1 / 1
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"We have previously shown that Uchl5 depletion enhances proteasomal substrate degradation in human U-2 OS (osteosarcoma) cells and that the C. elegans homolog UBH-4 regulates proteasome activity in C. elegans intestine, and affects the lifespan and health span of the animal (Matilainen et al., 2013)."