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CYLD activates p38 mitogen-activated protein kinase. 2 / 2
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"By using CYLD knock-out mice, a recent study shows that in TGF-beta-treated T cells, CYLD deficiency causes enhanced TAK1 and p38 mitogen activated protein kinase activities."

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"In an analysis of the mechanism of this finding, we noted first that TGF-beta-stimulated T cells lacking CYLD exhibit increased TAK1 and p38 mitogen activated protein kinase (MAP kinase) activity."