IndraLab

Statements

OTUB1 leads to the deubiquitination of DDX58. 2 / 2
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reach
"NS1 is the most important IFNs antagonist protein via mechanisms including inhibition of the TRIM25 mediated RIG-I ubiquitination, suppression of protein kinase R (PKR), phosphorylation of IkappaB kinases (IKK) alpha and beta in the NF-kappaB pathway, interruption of the phosphorylation of STAT1, STAT2, and STAT3 [XREF_BIBR, XREF_BIBR], and degradation of OTUB1 [XREF_BIBR]."
32235330
reach
"NS1 is the most important IFNs antagonist protein via mechanisms including inhibition of the TRIM25-mediated RIG-I ubiquitination, suppression of protein kinase R (PKR), phosphorylation of IκB kinases (IKK) α and β in the NF-κB pathway, interruption of the phosphorylation of STAT1, STAT2, and STAT3 [39, 115] , and degradation of OTUB1 [138] ."
32235330